Los Feliz, also Rancho Los Feliz ("Feliz Ranch") is a district of the City of Los Angeles, California, named for its land grantee José Vicente Feliz.

It lies north of East Hollywood and just south of the Santa Monica Mountains, adjacent to the neighborhoods of Hollywood and Silver Lake. It is home to the southern face of Griffith Park, which includes the Griffith Observatory and the Greek Theatre. Los Feliz is bordered by Hollywood on the south, Hyperion Avenue on the southeast, Griffith Park on the north, the Los Angeles River on the east, and Western Avenue on the west. It is traversed by Los Feliz Boulevard.

Los Feliz was home to many early movie studios, including the first Disney studio (now a Gelson's supermarket) and D. W. Griffith's studio; it currently is home to The Prospect Studios (formally known as First National-Warner Brothers and more recently ABC Television Center), at the intersection of Prospect Avenue and Talmadge Street. On Sunset Boulevard was Monogram Pictures (currently KCET public television) where early Charlie Chan movies were filmed.  The neighborhood has historically been home to movie stars, musicians, and the Hollywood elite. It boasts some of the best known residential architecture in the city, including two homes designed by Frank Lloyd Wright, Ennis House and the Hollyhock House, and Richard Neutra's Lovell House.